EdgeMarket › What Orbimed Advisors Llc reported owning

What Orbimed Advisors Llc reported owning

As filed on Form 13F for the quarter ending 2026-03-31, up to 45 days after that date. Long-only US-listed equity — shorts, bonds, cash and non-US listings are not on the form, so this is one leg of the book, not the book.

Reported value

5.0B

Positions

112

Quarter

2026-03-31

Shown below

50
largest by value
holdingvalue% of booksharesprice1y
EWTX
Edgewise Therapeutics, Inc.
488.8M9.7%15.5M44.18+219.2%
ELVN
Enliven Therapeutics, Inc.
312.0M6.2%8.0M59.82+204.3%
LLY
ELI LILLY & Co
217.8M4.3%236.8K1,255.40+78.0%
SVA
SINOVAC BIOTECH LTD
184.5M3.7%2.7M6.47+0.0%
BSX
BOSTON SCIENTIFIC CORP
149.5M3.0%2.4M50.37-52.5%
SION
Sionna Therapeutics, Inc.
141.5M2.8%3.5M5.29-76.8%
AZN
ASTRAZENECA PLC
132.2M2.6%670.2K165.98
MYGN
MYRIAD GENETICS INC
122.9M2.4%125.0M3.20-42.1%
MBX
MBX Biosciences, Inc.
108.6M2.2%3.6M66.33+386.6%
CRVS
Corvus Pharmaceuticals, Inc.
104.8M2.1%7.2M14.46+178.6%
ARGX
ARGENX SE
100.0M2.0%136.9K1,039.78+57.3%
EW
Edwards Lifesciences Corp
98.5M2.0%1.2M89.79+10.3%
ISRG
INTUITIVE SURGICAL INC
96.2M1.9%208.7K378.81-21.2%
CMPX
Compass Therapeutics, Inc.
80.5M1.6%15.2M2.40-13.7%
MRK
Merck & Co., Inc.
79.8M1.6%663.4K152.55+80.2%
GPCR
Structure Therapeutics Inc.
71.1M1.4%1.5M49.09+164.4%
AVBP
ArriVent BioPharma, Inc.
69.8M1.4%3.0M29.12+51.1%
IRON
Disc Medicine, Inc.
68.3M1.4%1.1M79.81+35.9%
SPRY
ARS Pharmaceuticals, Inc.
66.6M1.3%8.3M5.50-62.3%
CGON
CG Oncology, Inc.
64.2M1.3%948.3K79.81+212.6%
XENE
Xenon Pharmaceuticals Inc.
61.6M1.2%1.1M60.77+61.5%
SYK
STRYKER CORP
60.0M1.2%182.5K329.45-15.9%
BMY
BRISTOL MYERS SQUIBB CO
56.1M1.1%925.0K67.01+38.9%
MLYS
Mineralys Therapeutics, Inc.
55.6M1.1%2.1M25.65+65.7%
PRAX
Praxis Precision Medicines, Inc.
55.6M1.1%172.5K375.94+730.8%
PFE
PFIZER INC
54.7M1.1%1.9M28.07+10.6%
DYN
Dyne Therapeutics, Inc.
52.9M1.0%2.9M26.10+118.0%
NTRA
Natera, Inc.
52.4M1.0%262.0K332.03+106.7%
ABVX
Abivax S.A.
51.9M1.0%465.7K114.95+59.9%
UPB
Upstream Bio, Inc.
51.2M1.0%5.7M6.97-57.4%
DHR
DANAHER CORP /DE/
50.4M1.0%265.8K218.85+3.5%
CAI
Caris Life Sciences, Inc.
50.2M1.0%2.8M26.27-25.1%
RCEL
AVITA Medical, Inc.
42.5M0.8%41.0M10.06+114.5%
ASND
Ascendis Pharma A/S
41.6M0.8%182.0K253.29+31.4%
STTK
Shattuck Labs, Inc.
40.5M0.8%6.3M7.53+645.5%
GH
Guardant Health, Inc.
40.2M0.8%435.2K170.69+191.8%
ALNY
ALNYLAM PHARMACEUTICALS, INC.
39.4M0.8%119.0K236.22-48.5%
PRLD
Prelude Therapeutics Inc
37.3M0.7%10.9M6.63+531.4%
CRNX
Crinetics Pharmaceuticals, Inc.
36.3M0.7%999.0K84.69+191.1%
AXSM
Axsome Therapeutics, Inc.
36.2M0.7%213.9K207.77+77.6%
QURE
uniQure N.V.
34.9M0.7%2.1M48.37+212.5%
ORIC
Oric Pharmaceuticals, Inc.
34.1M0.7%2.7M14.20+49.3%
ELV
Elevance Health, Inc.
33.6M0.7%114.7K400.54+29.2%
RLMD
RELMADA THERAPEUTICS, INC.
32.8M0.7%4.7M4.63+655.9%
FBRX
Forte Biosciences, Inc.
31.0M0.6%1.2M76.92+554.1%
TRVI
Trevi Therapeutics, Inc.
29.3M0.6%2.5M17.96+142.0%
unmapped CUSIP 29664W10529.0M0.6%10.6M
NPCE
NeuroPace Inc
27.6M0.5%2.1M14.03+62.0%
RYTM
RHYTHM PHARMACEUTICALS, INC.
27.3M0.5%314.1K110.00+11.4%
TMO
THERMO FISHER SCIENTIFIC INC.
22.9M0.5%46.5K629.27+27.2%

A position that grew quarter on quarter may simply reflect a higher price: if the stock rose 40% and the manager did nothing, the reported value rose 40%. Reading that as accumulation is reading the price back to yourself. More on that →

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