EdgeMarketInstruments › SION

SION — Sionna Therapeutics, Inc.

US Healthcare Pharma & biotech equity mkt cap 239.2M
5.29 -4.08% today
USD · as of 2026-08-21

Price · 2025-02-07 → 2026-08-21

386 daily closes shown
52w low 4.50 · high 51.04

Anonymous view is capped at two years of history. A free account extends it to five, and Pro opens the whole archive back to 2025-02-07.

Performance

1 day-4.08%
1 week-18.11%
1 month-87.99%
3 months-87.33%
6 months-85.09%
Year to date-86.51%
1 year-76.77%

Technicals

RSI 1411.8
vs 50-day avg-85.35%
vs 200-day avg-86.30%
Volatility 1y122.7%
Max drawdown 1y-91.18%
Avg volume 30d3.1M
Daily bars held386
History from2025-02-07

Measured signals that fired on SION

datesignal measured base rate
2026-08-10Fair value gap, bearish
structure
-0.45% over 21 days · t = -3.29 · n = 108,591
statistically distinguishable from its control group
2026-08-10Bollinger bandwidth breaks out of its own compression
structure
-0.63% over 21 days · t = -2.80 · n = 7,196
statistically distinguishable from its control group
2026-08-04Breakout to a 52-week high
price
-1.00% over 21 days · t = -8.58 · n = 24,386
statistically distinguishable from its control group
2026-08-04Equal highs taken out
structure
-0.70% over 21 days · t = -8.28 · n = 68,636
statistically distinguishable from its control group
2026-07-17Breakout to a 52-week high
price
-1.00% over 21 days · t = -8.58 · n = 24,386
statistically distinguishable from its control group
2026-06-08Equal lows taken out
structure
-0.64% over 21 days · t = -4.75 · n = 55,661
statistically distinguishable from its control group

Excess return against a matched control group, on a point-in-time universe that includes delisted companies. Most families do not survive that. How the measurement works →

Insider transactions (Form 4)

dateinsiderwhatshares pricevalue
2026-07-07ORBIMED ADVISORS LLC
Director
Open-market sale 10b5-1 plan85.9K44.863.9M
2026-07-07Thompson Peter A.
Director
Open-market sale 10b5-1 plan85.9K44.863.9M
2026-07-07OrbiMed Capital GP VIII LLC
Director
Open-market sale 10b5-1 plan85.9K44.863.9M
2026-07-06Fitzpatrick Jennifer
Chief Legal Officer
Open-market sale 10b5-1 plan10.2K43.60446.9K
2026-07-06Fitzpatrick Jennifer
Chief Legal Officer
Option exercise 10b5-1 plan10.2K6.1162.6K
2026-06-30OrbiMed Capital GP VIII LLC
Director
Open-market sale 10b5-1 plan115.8K45.505.3M
2026-06-30ORBIMED ADVISORS LLC
Director
Open-market sale 10b5-1 plan115.8K45.505.3M
2026-06-30Thompson Peter A.
Director
Open-market sale 10b5-1 plan115.8K45.505.3M
2026-05-27OrbiMed Capital GP VIII LLC
Director
Open-market sale 10b5-1 plan10144.494.5K
2026-05-27ORBIMED ADVISORS LLC
Director
Open-market sale 10b5-1 plan10144.494.5K

Open-market purchases (code P) are the informative ones. Grants, option exercises and tax withholding are compensation mechanics, not decisions. How to read a Form 4 →

Largest institutional holders

managervalueshares
RA CAPITAL MANAGEMENT, L.P.397.1M9.9M
TPG GP A, LLC260.4M6.5M
ORBIMED ADVISORS LLC141.5M3.5M
VIKING GLOBAL INVESTORS LP128.1M3.2M
Atlas Venture Life Science Advisors, LLC120.1M3.0M
ENAVATE SCIENCES GP, LLC99.3M2.5M
JENNISON ASSOCIATES LLC58.2M1.5M
JPMORGAN CHASE & CO53.7M1.5M
BlackRock, Inc.52.0M1.3M
CITADEL ADVISORS LLC46.8M1.2M

13F positions as of 2026-03-31, filed up to 45 days after quarter end. Long-only US equity — shorts and derivatives never appear. What 13F does and does not show →

Latest SEC filings

formfiledperiod
8-K2026-08-102026-08-10on EDGAR ↗
10-Q2026-08-062026-06-30on EDGAR ↗
8-K2026-08-062026-08-06on EDGAR ↗
42026-07-092026-07-07on EDGAR ↗
42026-07-092026-07-07on EDGAR ↗
42026-07-072026-07-06on EDGAR ↗
1442026-07-06on EDGAR ↗
42026-07-022026-06-30on EDGAR ↗

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