MBX — MBX Biosciences, Inc.

US Healthcare Pharma & biotech equity mkt cap 3.2B
66.33 -0.09% today
USD · as of 2026-08-21

Price · 2024-09-13 → 2026-08-21

486 daily closes shown
52w low 9.74 · high 70.70

Anonymous view is capped at two years of history. A free account extends it to five, and Pro opens the whole archive back to 2024-09-13.

Performance

1 day-0.09%
1 week-3.27%
1 month+4.34%
3 months+108.65%
6 months+90.66%
Year to date+117.12%
1 year+386.65%

Technicals

RSI 1454.6
vs 50-day avg+12.90%
vs 200-day avg+71.22%
Volatility 1y130.8%
Max drawdown 1y-37.60%
Avg volume 30d582.1K
Daily bars held486
History from2024-09-13

Measured signals that fired on MBX

datesignal measured base rate
2026-08-04Breakout to a 52-week high
price
-1.00% over 21 days · t = -8.58 · n = 24,386
statistically distinguishable from its control group
2026-07-06Equal highs taken out
structure
-0.70% over 21 days · t = -8.28 · n = 68,636
statistically distinguishable from its control group
2026-06-22Breakout to a 52-week high
price
-1.00% over 21 days · t = -8.58 · n = 24,386
statistically distinguishable from its control group
2026-05-11Equal highs taken out
structure
-0.70% over 21 days · t = -8.28 · n = 68,636
statistically distinguishable from its control group
2026-05-08Fair value gap, bullish
structure
-0.67% over 21 days · t = -6.43 · n = 111,973
statistically distinguishable from its control group
2026-04-29Fair value gap, bearish
structure
-0.45% over 21 days · t = -3.29 · n = 108,591
statistically distinguishable from its control group

Excess return against a matched control group, on a point-in-time universe that includes delisted companies. Most families do not survive that. How the measurement works →

Insider transactions (Form 4)

dateinsiderwhatshares pricevalue
2026-08-04Azoulay Salomon
Chief Medical Officer
Open-market sale37065.7724.3K
2026-08-03Smither John W
Chief Financial Officer
Grant or award28.0K0.000
2026-08-03Hoerter Steven L.
President and CEO
Grant or award71.0K0.000
2026-05-08Azoulay Salomon
Chief Medical Officer
Open-market sale 10b5-1 plan55.0K38.382.1M
2026-05-08Azoulay Salomon
Chief Medical Officer
Option exercise 10b5-1 plan55.0K10.46575.3K
2026-05-08Azoulay Salomon
Chief Medical Officer
Open-market sale 10b5-1 plan15.0K38.30574.6K
2026-05-08Azoulay Salomon
Chief Medical Officer
Option exercise 10b5-1 plan15.0K16.00240.0K
2026-05-06Hawryluk P. Kent
President & CEO
Open-market sale60729.5417.9K
2026-05-06Azoulay Salomon
Chief Medical Officer
Open-market sale23129.546.8K
2026-05-01Hoerter Steven L.
Director
Grant or award11.9K0.000

Open-market purchases (code P) are the informative ones. Grants, option exercises and tax withholding are compensation mechanics, not decisions. How to read a Form 4 →

Largest institutional holders

managervalueshares
Frazier Life Sciences Management, L.P.198.6M6.7M
ORBIMED ADVISORS LLC108.6M3.6M
NEA Management Company, LLC107.9M3.6M
WELLINGTON MANAGEMENT GROUP LLP95.3M3.2M
BlackRock, Inc.87.8M2.9M
FMR LLC87.7M2.9M
Deep Track Capital, LP82.3M2.8M
NVP ASSOCIATES, LLC63.8M2.1M
Polar Capital Holdings Plc48.4M1.6M
BRAIDWELL LP44.6M1.5M

13F positions as of 2026-03-31, filed up to 45 days after quarter end. Long-only US equity — shorts and derivatives never appear. What 13F does and does not show →

Short selling

Avg short volume, 90d60.9% of tape
Days observed61

This is off-exchange short volume, not short interest: it is flow, not position, and 40–50% is normal because market makers short to fill your buy. Why that number misleads →

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