EdgeMarket › What Perceptive Advisors Llc reported owning

What Perceptive Advisors Llc reported owning

As filed on Form 13F for the quarter ending 2026-03-31, up to 45 days after that date. Long-only US-listed equity — shorts, bonds, cash and non-US listings are not on the form, so this is one leg of the book, not the book.

Reported value

5.1B

Positions

94

Quarter

2026-03-31

Shown below

50
largest by value
holdingvalue% of booksharesprice1y
PRAX
Praxis Precision Medicines, Inc.
656.0M12.8%2.0M375.94+730.8%
CELC
Celcuity Inc.
356.9M7.0%3.1M93.53+91.8%
ASND
Ascendis Pharma A/S
350.3M6.8%1.5M253.29+31.4%
ROIV
Roivant Sciences Ltd.
229.5M4.5%8.3M36.30+209.7%
unmapped CUSIP 152309100208.9M4.1%5.3M
RYTM
RHYTHM PHARMACEUTICALS, INC.
206.4M4.0%2.4M110.00+11.4%
SYRE
Spyre Therapeutics, Inc.
190.8M3.7%3.8M106.49+551.3%
unmapped CUSIP 670703107161.9M3.2%1.6M
EWTX
Edgewise Therapeutics, Inc.
139.4M2.7%4.4M44.18+219.2%
PTGX
Protagonist Therapeutics, Inc
129.7M2.5%1.2M154.32+174.4%
APGE
Apogee Therapeutics, Inc.
129.7M2.5%1.5M134.75+274.1%
TVTX
Travere Therapeutics, Inc.
123.1M2.4%4.1M65.71+265.7%
AMLX
Amylyx Pharmaceuticals, Inc.
115.2M2.3%8.3M38.66+381.4%
IMTX
Immatics N.V.
102.2M2.0%10.4M8.93+59.5%
RLAY
Relay Therapeutics, Inc.
97.0M1.9%9.8M19.44+471.8%
INBX
Inhibrx Biosciences, Inc.
97.0M1.9%1.4M103.63+324.5%
MGTX
MeiraGTx Holdings plc
89.3M1.7%10.3M14.34+89.7%
ZYME
Zymeworks Inc.
87.9M1.7%3.5M28.67+100.2%
SLDB
Solid Biosciences Inc.
85.7M1.7%11.9M9.30+64.3%
DYN
Dyne Therapeutics, Inc.
84.6M1.7%4.7M26.10+118.0%
BCRX
BIOCRYST PHARMACEUTICALS INC
70.8M1.4%7.4M9.55+14.0%
ORKA
Oruka Therapeutics, Inc.
68.4M1.3%1.4M107.96+649.7%
AORT
ARTIVION, INC.
60.0M1.2%1.6M28.08-34.7%
NRIX
Nurix Therapeutics, Inc.
57.5M1.1%3.7M26.72+180.4%
NAUT
Nautilus Biotechnology, Inc.
48.9M1.0%12.6M0.95+38.4%
CTMX
CytomX Therapeutics, Inc.
47.5M0.9%10.1M3.28+66.5%
ANRO
Alto Neuroscience, Inc.
45.2M0.9%2.0M34.28+899.4%
ENGN
enGene Therapeutics Inc.
39.7M0.8%5.8M1.78-53.9%
IMVT
Immunovant, Inc.
39.7M0.8%1.6M44.37+199.4%
ISRG
INTUITIVE SURGICAL INC
39.4M0.8%85.4K378.81-21.2%
IONS
IONIS PHARMACEUTICALS INC
37.8M0.7%504.0K59.74+39.5%
unmapped CUSIP 23954D10937.6M0.7%1.8M
ABVX
Abivax S.A.
36.6M0.7%328.9K114.95+59.9%
CRVS
Corvus Pharmaceuticals, Inc.
33.5M0.7%2.3M14.46+178.6%
RGEN
REPLIGEN CORP
33.1M0.6%280.5K181.13+49.0%
JAZZ
Jazz Pharmaceuticals plc
32.1M0.6%170.0K254.28+113.6%
DMRA
Damora Therapeutics, Inc.
31.7M0.6%1.2M30.82+811.9%
XFOR
X4 Pharmaceuticals, Inc
27.8M0.5%6.7M4.04+44.3%
GH
Guardant Health, Inc.
27.7M0.5%300.0K170.69+191.8%
DRUG
BRIGHT MINDS BIOSCIENCES INC.
27.5M0.5%377.5K77.42+80.0%
IVVD
Invivyd, Inc.
27.1M0.5%20.9M1.00+57.2%
SION
Sionna Therapeutics, Inc.
26.4M0.5%658.4K5.29-76.8%
AXSM
Axsome Therapeutics, Inc.
25.3M0.5%149.9K207.77+77.6%
RVMD
Revolution Medicines, Inc.
25.1M0.5%258.6K209.46+479.3%
SABS
SAB Biotherapeutics, Inc.
24.6M0.5%6.4M3.78+88.1%
BLTE
BELITE BIO, INC
24.2M0.5%152.0K161.06+154.0%
TENX
TENAX THERAPEUTICS, INC.
23.2M0.5%1.4M1.75-70.7%
AXGN
Axogen, Inc.
23.1M0.5%697.3K50.40+223.9%
VRDN
Viridian Therapeutics, Inc.\DE
22.9M0.4%1.2M24.29+33.9%
OBIO
Orchestra BioMed Holdings, Inc.
21.4M0.4%5.0M5.36+120.6%

A position that grew quarter on quarter may simply reflect a higher price: if the stock rose 40% and the manager did nothing, the reported value rose 40%. Reading that as accumulation is reading the price back to yourself. More on that →

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