EdgeMarketInstruments › AMLX

AMLX — Amylyx Pharmaceuticals, Inc.

US Healthcare Pharma & biotech equity mkt cap 4.4B
38.66 -2.52% today
USD · as of 2026-08-21

Price · 2024-08-26 → 2026-08-21

499 daily closes shown
52w low 8.43 · high 39.66

Anonymous view is capped at two years of history. A free account extends it to five, and Pro opens the whole archive back to 2022-01-07.

Performance

1 day-2.52%
1 week+78.73%
1 month+119.78%
3 months+177.53%
6 months+175.95%
Year to date+238.53%
1 year+381.44%
3 years+93.16%

Technicals

RSI 1483.1
vs 50-day avg+90.75%
vs 200-day avg+145.69%
Volatility 1y89.4%
Max drawdown 1y-30.61%
Avg volume 30d3.1M
Daily bars held1,159
History from2022-01-07

Measured signals that fired on AMLX

datesignal measured base rate
2026-08-14Fair value gap, bearish
structure
-0.45% over 21 days · t = -3.29 · n = 108,591
statistically distinguishable from its control group
2026-08-05Fair value gap, bullish
structure
-0.67% over 21 days · t = -6.43 · n = 111,973
statistically distinguishable from its control group
2026-08-04Breakout to a 52-week high
price
-1.00% over 21 days · t = -8.58 · n = 24,386
statistically distinguishable from its control group
2026-08-03Bollinger bandwidth breaks out of its own compression
structure
-0.63% over 21 days · t = -2.80 · n = 7,196
statistically distinguishable from its control group
2026-07-28Bollinger bandwidth breaks out of its own compression
structure
-0.63% over 21 days · t = -2.80 · n = 7,196
statistically distinguishable from its control group
2026-06-29Equal highs taken out
structure
-0.70% over 21 days · t = -8.28 · n = 68,636
statistically distinguishable from its control group

Excess return against a matched control group, on a point-in-time universe that includes delisted companies. Most families do not survive that. How the measurement works →

Insider transactions (Form 4)

dateinsiderwhatshares pricevalue
2026-08-18Klee Justin B.
Co-Chief Executive Officer
Grant or award60.0K0.000
2026-08-18Cohen Joshua B
Co-Chief Executive Officer
Grant or award60.0K0.000
2026-08-18Bedrosian Camille L
Chief Medical Officer
Grant or award22.8K0.000
2026-08-18FRATES JAMES M
Chief Financial Officer
Grant or award22.8K0.000
2026-08-18Mazzariello Gina
Chief Legal Officer
Grant or award21.3K0.000
2026-07-10Mazzariello Gina
Chief Legal Officer
Open-market sale 10b5-1 plan15.0K17.61264.1K
2026-07-09Mazzariello Gina
Chief Legal Officer
Open-market sale 10b5-1 plan15.0K18.32274.7K
2026-05-21Firestone Karen
Director
Open-market purchase3.8K13.5151.3K
2026-03-05Mazzariello Gina
Chief Legal Officer
Grant or award74.7K0.000
2026-03-05Cohen Joshua B
Co-Chief Executive Officer
Grant or award248.9K0.000

Open-market purchases (code P) are the informative ones. Grants, option exercises and tax withholding are compensation mechanics, not decisions. How to read a Form 4 →

Largest institutional holders

managervalueshares
FMR LLC231.2M16.6M
BlackRock, Inc.122.7M8.8M
PERCEPTIVE ADVISORS LLC115.2M8.3M
TCG Crossover Management, LLC86.8M6.2M
Commodore Capital LP78.5M5.7M
JANUS HENDERSON GROUP PLC69.3M5.0M
Saturn V Capital Management LP60.5M4.3M
VANGUARD CAPITAL MANAGEMENT LLC57.6M4.1M
ADAGE CAPITAL PARTNERS GP, L.L.C.49.5M3.6M
First Light Asset Management, LLC44.3M3.2M

13F positions as of 2026-03-31, filed up to 45 days after quarter end. Long-only US equity — shorts and derivatives never appear. What 13F does and does not show →

Short selling

Avg short volume, 90d48.7% of tape
Days observed61

This is off-exchange short volume, not short interest: it is flow, not position, and 40–50% is normal because market makers short to fill your buy. Why that number misleads →

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