EdgeMarketInstruments › TYRA

TYRA — Tyra Biosciences, Inc.

US Healthcare Pharma & biotech equity mkt cap 1.6B
26.05 +1.40% today
USD · as of 2026-08-21

Price · 2024-08-26 → 2026-08-21

499 daily closes shown
52w low 11.70 · high 39.61

Anonymous view is capped at two years of history. A free account extends it to five, and Pro opens the whole archive back to 2021-09-15.

Performance

1 day+1.40%
1 week+3.01%
1 month-15.42%
3 months-21.11%
6 months-17.51%
Year to date-2.76%
1 year+154.39%
3 years+74.95%

Technicals

RSI 1429.2
vs 50-day avg-12.08%
vs 200-day avg-12.49%
Volatility 1y63.0%
Max drawdown 1y-36.83%
Avg volume 30d593.5K
Daily bars held1,239
History from2021-09-15

Measured signals that fired on TYRA

datesignal measured base rate
2026-08-14Equal lows taken out
structure
-0.64% over 21 days · t = -4.75 · n = 55,661
statistically distinguishable from its control group
2026-08-06Fair value gap, bearish
structure
-0.45% over 21 days · t = -3.29 · n = 108,591
statistically distinguishable from its control group
2026-08-05Bollinger bandwidth breaks out of its own compression
structure
-0.63% over 21 days · t = -2.80 · n = 7,196
statistically distinguishable from its control group
2026-06-08Equal lows taken out
structure
-0.64% over 21 days · t = -4.75 · n = 55,661
statistically distinguishable from its control group
2026-06-02Fair value gap, bearish
structure
-0.45% over 21 days · t = -3.29 · n = 108,591
statistically distinguishable from its control group
2026-04-01Fair value gap, bullish
structure
-0.67% over 21 days · t = -6.43 · n = 111,973
statistically distinguishable from its control group

Excess return against a matched control group, on a point-in-time universe that includes delisted companies. Most families do not survive that. How the measurement works →

Insider transactions (Form 4)

dateinsiderwhatshares pricevalue
2026-05-05Ashar Bhavesh
Chief Operating Officer
Grant or award15.0K0.000
2026-05-05Fuhrman Alan
Chief Financial Officer
Grant or award20.0K0.000
2026-05-05Rueb Yuliya
Vice President, Finance (PAO)
Grant or award8.3K0.000
2026-05-05Warner Douglas J
Chief Medical Officer
Grant or award25.0K0.000
2026-05-05Harris Todd
President and CEO
Grant or award79.0K0.000
2026-03-26KAPLAN GILLA
Director
Disposition to issuer53.2K37.752.0M
2026-03-26KAPLAN GILLA
Director
Option exercise53.2K2.25119.6K
2026-03-25KAPLAN GILLA
Director
Open-market sale14.3K36.97528.5K
2026-03-25KAPLAN GILLA
Director
Option exercise14.3K2.2532.2K
2026-03-13Harris Todd
President and CEO
Grant or award1.5K9.1313.4K

Open-market purchases (code P) are the informative ones. Grants, option exercises and tax withholding are compensation mechanics, not decisions. How to read a Form 4 →

Largest institutional holders

managervalueshares
RA CAPITAL MANAGEMENT, L.P.467.2M12.2M
FMR LLC296.7M7.7M
Nextech Invest, Ltd.155.3M4.1M
JANUS HENDERSON GROUP PLC148.9M3.9M
Alta Partners Management Company, L.P.146.4M3.8M
FARALLON CAPITAL MANAGEMENT LLC137.1M3.6M
TCG Crossover Management, LLC124.4M3.2M
Commodore Capital LP94.8M2.5M
BlackRock, Inc.84.9M2.2M
Paradigm Biocapital Advisors LP78.7M2.1M

13F positions as of 2026-03-31, filed up to 45 days after quarter end. Long-only US equity — shorts and derivatives never appear. What 13F does and does not show →

Short selling

Avg short volume, 90d63.5% of tape
Days observed61

This is off-exchange short volume, not short interest: it is flow, not position, and 40–50% is normal because market makers short to fill your buy. Why that number misleads →

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