SEPN — Septerna, Inc.
Price · 2024-10-25 → 2026-08-21
456 daily closes shownAnonymous view is capped at two years of history. A free account extends it to five, and Pro opens the whole archive back to 2024-10-25.
Performance
Technicals
Others in Healthcare
Measured signals that fired on SEPN
| date | signal | measured base rate |
|---|---|---|
| 2026-08-21 | Fair value gap, bearish structure | -0.45% over 21 days · t = -3.29 · n = 108,591 statistically distinguishable from its control group |
| 2026-08-14 | Cluster sale: three or more insiders insider | -0.37% over 21 days · t = -3.38 · n = 21,542 statistically distinguishable from its control group |
| 2026-08-07 | Equal highs taken out structure | -0.70% over 21 days · t = -8.28 · n = 68,636 statistically distinguishable from its control group |
| 2026-08-05 | Fair value gap, bullish structure | -0.67% over 21 days · t = -6.43 · n = 111,973 statistically distinguishable from its control group |
| 2026-08-04 | Breakout to a 52-week high price | -1.00% over 21 days · t = -8.58 · n = 24,386 statistically distinguishable from its control group |
| 2026-05-28 | Breakout to a 52-week high price | -1.00% over 21 days · t = -8.58 · n = 24,386 statistically distinguishable from its control group |
Excess return against a matched control group, on a point-in-time universe that includes delisted companies. Most families do not survive that. How the measurement works →
Insider transactions (Form 4)
| date | insider | what | shares | price | value |
|---|---|---|---|---|---|
| 2026-08-12 | RA Capital Healthcare Fund LP Director | Open-market sale | 746.5K | 42.50 | 31.7M |
| 2026-08-12 | RA CAPITAL MANAGEMENT, L.P. Director | Open-market sale | 746.5K | 42.50 | 31.7M |
| 2026-08-12 | RA CAPITAL MANAGEMENT, L.P. Director | Open-market sale | 746.5K | 42.50 | 31.7M |
| 2026-08-12 | Kolchinsky Peter Director | Open-market sale | 746.5K | 42.50 | 31.7M |
| 2026-08-12 | Kolchinsky Peter Director | Open-market sale | 746.5K | 42.50 | 31.7M |
| 2026-08-12 | Shah Rajeev M. Director | Open-market sale | 746.5K | 42.50 | 31.7M |
| 2026-08-12 | Shah Rajeev M. Director | Open-market sale | 746.5K | 42.50 | 31.7M |
| 2026-08-12 | RA Capital Nexus Fund III, L.P. Director | Open-market sale | 746.5K | 42.50 | 31.7M |
| 2026-08-12 | RA Capital Nexus Fund III, L.P. Director | Open-market sale | 746.5K | 42.50 | 31.7M |
| 2026-08-12 | RA Capital Healthcare Fund LP Director | Open-market sale | 746.5K | 42.50 | 31.7M |
Open-market purchases (code P) are the informative ones. Grants, option exercises and tax withholding are compensation mechanics, not decisions. How to read a Form 4 →
Largest institutional holders
| manager | value | shares |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 168.1M | 7.0M |
| TRV GP V, LLC | 149.4M | 6.2M |
| Driehaus Capital Management LLC | 105.6M | 4.4M |
| TRV GP VI, LLC | 101.2M | 4.2M |
| SAMSARA BIOCAPITAL, LLC | 75.7M | 3.1M |
| GOLDMAN SACHS GROUP INC | 69.8M | 2.9M |
| Siren, L.L.C. | 48.1M | 2.0M |
| BlackRock, Inc. | 43.8M | 1.8M |
| BVF INC/IL | 32.5M | 1.4M |
| Avoro Capital Advisors LLC | 32.1M | 1.3M |
13F positions as of 2026-03-31, filed up to 45 days after quarter end. Long-only US equity — shorts and derivatives never appear. What 13F does and does not show →
Short selling
This is off-exchange short volume, not short interest: it is flow, not position, and 40–50% is normal because market makers short to fill your buy. Why that number misleads →
Recent headlines
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