EdgeMarketInstruments › PYXS

PYXS — Pyxis Oncology, Inc.

US Healthcare Pharma & biotech equity mkt cap 260.2M
3.08 -1.28% today
USD · as of 2026-08-21

Price · 2024-08-26 → 2026-08-21

499 daily closes shown
52w low 1.06 · high 5.34

Anonymous view is capped at two years of history. A free account extends it to five, and Pro opens the whole archive back to 2021-10-08.

Performance

1 day-1.28%
1 week+2.33%
1 month+14.93%
3 months+58.76%
6 months+116.90%
Year to date+167.83%
1 year+165.52%
3 years+29.41%

Technicals

RSI 1450.6
vs 50-day avg+15.19%
vs 200-day avg+32.79%
Volatility 1y130.2%
Max drawdown 1y-80.15%
Avg volume 30d1.3M
Daily bars held1,222
History from2021-10-08

Measured signals that fired on PYXS

datesignal measured base rate
2026-06-11Short volume far above its own normal
short
-0.76% over 21 days · t = -2.79 · n = 5,897
statistically distinguishable from its control group
2026-03-05Short volume far above its own normal
short
-0.76% over 21 days · t = -2.79 · n = 5,897
statistically distinguishable from its control group

Excess return against a matched control group, on a point-in-time universe that includes delisted companies. Most families do not survive that. How the measurement works →

Insider transactions (Form 4)

dateinsiderwhatshares pricevalue
2026-06-30Dupont Jakob
Director
Open-market sale 10b5-1 plan35.0K3.06107.1K
2026-06-30Dupont Jakob
Director
Option exercise 10b5-1 plan35.0K1.6056.0K
2026-03-24Wadhane Jitendra
Prin Fin & Acct Officer
Grant or award109.5K0.000
2025-04-21HUMPHREY RACHEL
Director
Open-market sale 10b5-1 plan13.9K1.0314.3K
2025-04-17HUMPHREY RACHEL
Director
Open-market sale 10b5-1 plan2000.97194
2025-04-14HUMPHREY RACHEL
Director
Open-market sale 10b5-1 plan1.4K0.971.4K
2024-11-26Connealy Pamela Ann
CFO & COO
Open-market purchase83.4K1.96163.5K
2024-11-26Connealy Pamela Ann
CFO & COO
Open-market purchase5.5K2.0010.9K
2024-06-07Palani Santhosh
Director
Grant or award6.0K0.000
2024-03-26Cline Darren S
Director
Grant or award35.2K0.000

Open-market purchases (code P) are the informative ones. Grants, option exercises and tax withholding are compensation mechanics, not decisions. How to read a Form 4 →

Largest institutional holders

managervalueshares
Pfizer Inc9.2M7.0M
Laurion Capital Management LP7.3M5.0M
GordonMD Global Investments LP6.0M4.1M
VANGUARD CAPITAL MANAGEMENT LLC3.0M2.0M
Atle Fund Management AB1.6M197.0K
Palo Alto Investors LP1.5M1.0M
683 Capital Management, LLC1.3M896.3K
RENAISSANCE TECHNOLOGIES LLC1.3M888.7K
BlackRock, Inc.1.2M788.8K
GEODE CAPITAL MANAGEMENT, LLC873.8K598.1K

13F positions as of 2026-03-31, filed up to 45 days after quarter end. Long-only US equity — shorts and derivatives never appear. What 13F does and does not show →

Latest SEC filings

formfiledperiod
42026-08-202026-08-20on EDGAR ↗
S-32026-08-20on EDGAR ↗
42026-08-142026-08-12on EDGAR ↗
10-Q2026-08-132026-06-30on EDGAR ↗
8-K2026-08-132026-08-13on EDGAR ↗
32026-07-102026-06-30on EDGAR ↗
SCHEDULE 13G2026-07-10on EDGAR ↗
42026-07-022026-06-30on EDGAR ↗

Short selling

Avg short volume, 90d51.8% of tape
Days observed61

This is off-exchange short volume, not short interest: it is flow, not position, and 40–50% is normal because market makers short to fill your buy. Why that number misleads →

Recent headlines

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