EdgeMarketInstruments › MIST

MIST — Milestone Pharmaceuticals Inc.

US Healthcare Pharma & biotech equity mkt cap 131.3M
1.05 +2.43% today
USD · as of 2026-08-21

Price · 2024-08-26 → 2026-08-21

499 daily closes shown
52w low 1.01 · high 2.95

Anonymous view is capped at two years of history. A free account extends it to five, and Pro opens the whole archive back to 2019-05-09.

Performance

1 day+2.43%
1 week-4.09%
1 month-12.08%
3 months-30.59%
6 months-37.94%
Year to date-48.54%
1 year-35.67%
3 years-65.75%
5 years-80.64%

Technicals

RSI 1444.0
vs 50-day avg-12.93%
vs 200-day avg-37.94%
Volatility 1y71.3%
Max drawdown 1y-65.76%
Avg volume 30d1.5M
Daily bars held1,832
History from2019-05-09

Measured signals that fired on MIST

datesignal measured base rate
2026-05-07Short volume far above its own normal
short
-0.76% over 21 days · t = -2.79 · n = 5,897
statistically distinguishable from its control group
2026-04-09Equal highs taken out
structure
-0.70% over 21 days · t = -8.28 · n = 68,636
statistically distinguishable from its control group

Excess return against a matched control group, on a point-in-time universe that includes delisted companies. Most families do not survive that. How the measurement works →

Insider transactions (Form 4)

dateinsiderwhatshares pricevalue
2026-04-16Oliveto Joseph
President and CEO
Open-market sale 10b5-1 plan36.5K2.2682.5K
2026-01-26Oliveto Joseph
President and CEO
Open-market sale34.5K1.9366.6K
2026-01-26Bharucha David
Chief Medical Officer
Open-market sale12.2K1.9323.6K
2026-01-26Hasija Amit
CFO & EVP of Corp. Development
Open-market sale12.2K1.9323.6K
2026-01-26Nelson Jeffrey Edward
Chief Operating Officer
Open-market sale12.2K1.9323.6K
2026-01-26Muller Lorenz
Chief Commercial Officer
Open-market sale11.2K1.9321.6K
2026-01-26Hasija Amit
CFO & EVP of Corp. Development
Option exercise20.1K
2026-01-26Bharucha David
Chief Medical Officer
Option exercise20.1K
2026-01-26Muller Lorenz
Chief Commercial Officer
Option exercise20.1K
2026-01-26Nelson Jeffrey Edward
Chief Operating Officer
Option exercise20.1K

Open-market purchases (code P) are the informative ones. Grants, option exercises and tax withholding are compensation mechanics, not decisions. How to read a Form 4 →

Largest institutional holders

managervalueshares
RTW INVESTMENTS, LP7.5M6.3M
Propel Bio Management, LLC5.1M4.1M
TWO SIGMA INVESTMENTS, LP2.8M2.3M
GOLDMAN SACHS GROUP INC2.4M2.0M
MARSHALL WACE, LLP2.3M1.9M
MILLENNIUM MANAGEMENT LLC1.8M1.5M
Simplify Asset Management Inc.1.8M1.5M
Point72 Asset Management, L.P.1.3M1.1M
Balyasny Asset Management L.P.1.0M851.3K
Lion Point Capital, LP975.8K820.0K

13F positions as of 2026-03-31, filed up to 45 days after quarter end. Long-only US equity — shorts and derivatives never appear. What 13F does and does not show →

Latest SEC filings

formfiledperiod
8-K2026-08-122026-08-12on EDGAR ↗
10-Q2026-08-122026-06-30on EDGAR ↗
SCHEDULE 13G2026-08-07on EDGAR ↗
8-K2026-06-152026-06-10on EDGAR ↗
42026-06-122026-06-10on EDGAR ↗
42026-06-122026-06-10on EDGAR ↗
42026-06-122026-06-10on EDGAR ↗
42026-06-122026-06-10on EDGAR ↗

Short selling

Avg short volume, 90d59.7% of tape
Days observed61

This is off-exchange short volume, not short interest: it is flow, not position, and 40–50% is normal because market makers short to fill your buy. Why that number misleads →

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