EdgeMarketInstruments › MDGL

MDGL — MADRIGAL PHARMACEUTICALS, INC.

US Healthcare Pharma & biotech equity mkt cap 12.0B
516.74 -0.45% today
USD · as of 2026-08-21

Price · 2024-08-26 → 2026-08-21

499 daily closes shown
52w low 407.09 · high 602.83

Anonymous view is capped at two years of history. A free account extends it to five, and Pro opens the whole archive back to 2016-01-04.

Performance

1 day-0.45%
1 week+1.81%
1 month-4.90%
3 months+0.61%
6 months+18.79%
Year to date-12.99%
1 year+31.94%
3 years+194.25%
5 years+508.93%

Technicals

RSI 1461.7
vs 50-day avg-1.16%
vs 200-day avg+0.56%
Volatility 1y44.4%
Max drawdown 1y-29.36%
Avg volume 30d349.4K
Daily bars held2,674
History from2016-01-04

Measured signals that fired on MDGL

datesignal measured base rate
2026-08-14Fair value gap, bearish
structure
-0.45% over 21 days · t = -3.29 · n = 108,591
statistically distinguishable from its control group
2026-08-05Fair value gap, bullish
structure
-0.67% over 21 days · t = -6.43 · n = 111,973
statistically distinguishable from its control group
2026-07-30Fair value gap, bearish
structure
-0.45% over 21 days · t = -3.29 · n = 108,591
statistically distinguishable from its control group
2026-06-26Volume shock without a price move
price
-1.33% over 21 days · t = -4.53 · n = 16,432
statistically distinguishable from its control group
2026-06-01Fair value gap, bearish
structure
-0.45% over 21 days · t = -3.29 · n = 108,591
statistically distinguishable from its control group
2026-03-27Fair value gap, bullish
structure
-0.67% over 21 days · t = -6.43 · n = 111,973
statistically distinguishable from its control group

Excess return against a matched control group, on a point-in-time universe that includes delisted companies. Most families do not survive that. How the measurement works →

Insider transactions (Form 4)

dateinsiderwhatshares pricevalue
2026-08-17Kelley Shannon T
General Counsel
Open-market sale664514.97341.9K
2026-08-15REED JOHN C
Director
Grant or award6470.000
2026-07-20Sibold William John
President and CEO
Open-market sale680547.70372.4K
2026-07-20Sibold William John
President and CEO
Open-market sale545544.71296.9K
2026-07-20Sibold William John
President and CEO
Open-market sale280555.05155.4K
2026-07-20Sibold William John
President and CEO
Open-market sale275545.71150.1K
2026-07-20Sibold William John
President and CEO
Open-market sale269547.08147.2K
2026-07-20Sibold William John
President and CEO
Open-market sale153550.0184.2K
2026-07-20Sibold William John
President and CEO
Open-market sale140542.7576.0K
2026-07-20Sibold William John
President and CEO
Open-market sale110543.7959.8K

Open-market purchases (code P) are the informative ones. Grants, option exercises and tax withholding are compensation mechanics, not decisions. How to read a Form 4 →

Largest institutional holders

managervalueshares
BAKER BROS. ADVISORS LP1.1B2.1M
JANUS HENDERSON GROUP PLC1.1B2.0M
RTW INVESTMENTS, LP1.0B2.0M
Avoro Capital Advisors LLC951.8M1.8M
BlackRock, Inc.816.6M1.6M
PAULSON & CO. INC.728.8M1.4M
VANGUARD PORTFOLIO MANAGEMENT LLC440.3M841.1K
VANGUARD CAPITAL MANAGEMENT LLC433.0M827.1K
WELLINGTON MANAGEMENT GROUP LLP363.8M695.0K
STATE STREET CORP319.1M609.5K

13F positions as of 2026-03-31, filed up to 45 days after quarter end. Long-only US equity — shorts and derivatives never appear. What 13F does and does not show →

Short selling

Avg short volume, 90d53.5% of tape
Days observed61

This is off-exchange short volume, not short interest: it is flow, not position, and 40–50% is normal because market makers short to fill your buy. Why that number misleads →

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