EdgeMarket › What Frazier Life Sciences Management, L.P. reported owning

What Frazier Life Sciences Management, L.P. reported owning

As filed on Form 13F for the quarter ending 2026-03-31, up to 45 days after that date. Long-only US-listed equity — shorts, bonds, cash and non-US listings are not on the form, so this is one leg of the book, not the book.

Reported value

3.9B

Positions

38

Quarter

2026-03-31

Shown below

38
largest by value
holdingvalue% of booksharesprice1y
MIRM
Mirum Pharmaceuticals, Inc.
709.4M18.3%7.7M96.31+44.4%
NAMS
NewAmsterdam Pharma Co N.V.
542.4M14.0%16.9M27.87+14.6%
ERAS
Erasca, Inc.
399.2M10.3%24.7M17.63+1107.5%
BBIO
BridgeBio Pharma, Inc.
256.1M6.6%3.4M81.50+66.7%
ARQT
Arcutis Biotherapeutics, Inc.
232.6M6.0%9.9M25.08+58.8%
MBX
MBX Biosciences, Inc.
198.6M5.1%6.7M66.33+386.6%
PHAT
Phathom Pharmaceuticals, Inc.
138.5M3.6%12.5M8.87-16.6%
MAZE
Maze Therapeutics, Inc.
136.3M3.5%4.6M29.43+118.3%
KRYS
Krystal Biotech, Inc.
124.3M3.2%481.3K346.58+137.6%
TRVI
Trevi Therapeutics, Inc.
118.6M3.1%9.9M17.96+142.0%
PVLA
PALVELLA THERAPEUTICS, INC.
110.0M2.8%882.4K142.04+181.6%
unmapped CUSIP 48349710399.9M2.6%5.0M
IRON
Disc Medicine, Inc.
86.6M2.2%1.4M79.81+35.9%
CYTK
CYTOKINETICS INC
76.4M2.0%1.2M76.84+105.9%
RVMD
Revolution Medicines, Inc.
65.7M1.7%675.7K209.46+479.3%
DYN
Dyne Therapeutics, Inc.
57.2M1.5%3.2M26.10+118.0%
SVRA
Savara Inc
53.1M1.4%9.7M5.59+80.9%
TARS
Tarsus Pharmaceuticals, Inc.
51.1M1.3%728.6K72.70+31.2%
VOR
Vor Biopharma Inc.
45.4M1.2%2.5M23.36-46.9%
AGIO
AGIOS PHARMACEUTICALS, INC.
42.5M1.1%1.3M33.09-10.1%
BCRX
BIOCRYST PHARMACEUTICALS INC
38.2M1.0%4.0M9.55+14.0%
ZLAB
Zai Lab Ltd
35.8M0.9%1.9M26.01-22.4%
AURA
Aura Biosciences, Inc.
34.1M0.9%5.1M7.80+22.4%
ACAD
ACADIA PHARMACEUTICALS INC
32.0M0.8%1.4M29.50+18.3%
ASND
Ascendis Pharma A/S
30.5M0.8%133.3K253.29+31.4%
LXEO
Lexeo Therapeutics, Inc.
25.4M0.7%4.4M4.88+1.7%
ALKS
Alkermes plc.
24.8M0.6%700.6K48.33+66.8%
ACRS
Aclaris Therapeutics, Inc.
18.5M0.5%4.9M6.41+254.1%
GLUE
Monte Rosa Therapeutics, Inc.
16.4M0.4%1.0M14.30+222.8%
IMCR
Immunocore Holdings plc
14.6M0.4%484.8K36.88+13.5%
MNKD
MANNKIND CORP
14.5M0.4%5.9M4.15+4.5%
VALN
Valneva SE
14.3M0.4%2.3M6.96-39.5%
EOLS
Evolus, Inc.
10.8M0.3%2.6M8.39+16.0%
unmapped CUSIP N6250911710.0M0.3%500.3K
ALLO
Allogene Therapeutics, Inc.
9.3M0.2%3.8M2.09+97.2%
AUTL
Autolus Therapeutics plc
6.1M0.2%4.4M2.41+39.3%
IBIO
iBio, Inc.
3.7M0.1%2.0M1.43+88.2%
XLO
Xilio Therapeutics, Inc.
3.6M0.1%422.5K9.23-0.6%

A position that grew quarter on quarter may simply reflect a higher price: if the stock rose 40% and the manager did nothing, the reported value rose 40%. Reading that as accumulation is reading the price back to yourself. More on that →

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