EdgeMarket › What Paradigm Biocapital Advisors Lp reported owning

What Paradigm Biocapital Advisors Lp reported owning

As filed on Form 13F for the quarter ending 2026-03-31, up to 45 days after that date. Long-only US-listed equity — shorts, bonds, cash and non-US listings are not on the form, so this is one leg of the book, not the book.

Reported value

4.9B

Positions

35

Quarter

2026-03-31

Shown below

35
largest by value
holdingvalue% of booksharesprice1y
unmapped CUSIP 03940C100663.0M13.5%5.8M
RVMD
Revolution Medicines, Inc.
647.3M13.2%6.7M209.46+479.3%
unmapped CUSIP 670703107545.5M11.1%5.3M
PCVX
Vaxcyte, Inc.
278.5M5.7%4.8M62.62+100.3%
EWTX
Edgewise Therapeutics, Inc.
232.0M4.7%7.4M44.18+219.2%
GMAB
GENMAB A/S
213.8M4.4%8.0M33.45+39.0%
INSM
INSMED Inc
205.1M4.2%1.3M125.77-2.8%
TARS
Tarsus Pharmaceuticals, Inc.
179.7M3.7%2.6M72.70+31.2%
BLTE
BELITE BIO, INC
177.7M3.6%1.1M161.06+154.0%
ERAS
Erasca, Inc.
168.2M3.4%10.4M17.63+1107.5%
unmapped CUSIP 152309100142.0M2.9%3.6M
OLMA
Olema Pharmaceuticals, Inc.
119.6M2.4%8.0M10.69+96.1%
unmapped CUSIP 880881107116.9M2.4%2.2M
ORKA
Oruka Therapeutics, Inc.
113.8M2.3%2.3M107.96+649.7%
APGE
Apogee Therapeutics, Inc.
113.5M2.3%1.3M134.75+274.1%
SYRE
Spyre Therapeutics, Inc.
98.7M2.0%2.0M106.49+551.3%
CYTK
CYTOKINETICS INC
97.6M2.0%1.5M76.84+105.9%
ABVX
Abivax S.A.
86.0M1.8%772.5K114.95+59.9%
TNGX
Tango Therapeutics, Inc.
83.9M1.7%4.0M23.88+253.8%
MAZE
Maze Therapeutics, Inc.
81.9M1.7%2.7M29.43+118.3%
TYRA
Tyra Biosciences, Inc.
78.7M1.6%2.1M26.05+154.4%
VRDN
Viridian Therapeutics, Inc.\DE
61.6M1.3%3.1M24.29+33.9%
SRRK
Scholar Rock Holding Corp
60.3M1.2%1.2M56.50+64.2%
MIRM
Mirum Pharmaceuticals, Inc.
57.7M1.2%625.0K96.31+44.4%
EYPT
EyePoint, Inc.
40.5M0.8%3.1M5.32-53.8%
LXEO
Lexeo Therapeutics, Inc.
35.5M0.7%6.2M4.88+1.7%
MANE
Veradermics, Inc
33.2M0.7%525.0K102.82
VOR
Vor Biopharma Inc.
31.2M0.6%1.8M23.36-46.9%
URGN
UroGen Pharma Ltd.
30.6M0.6%1.7M46.86+142.7%
GPCR
Structure Therapeutics Inc.
26.3M0.5%545.3K49.09+164.4%
IVA
Inventiva S.A.
22.2M0.5%4.0M4.68+2.2%
ORIC
Oric Pharmaceuticals, Inc.
21.6M0.4%1.7M14.20+49.3%
ASMB
ASSEMBLY BIOSCIENCES, INC.
18.5M0.4%665.3K34.38+31.5%
BBOT
BridgeBio Oncology Therapeutics, Inc.
7.8M0.2%868.2K9.08-5.7%
KLRS
Kalaris Therapeutics, Inc.
4.0M0.1%700.0K4.15+61.5%

A position that grew quarter on quarter may simply reflect a higher price: if the stock rose 40% and the manager did nothing, the reported value rose 40%. Reading that as accumulation is reading the price back to yourself. More on that →

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